OVERVIEW

Human Chorionic Gonadotropin (HCG) is a naturally occurring glycoprotein hormone primarily produced during pregnancy. It plays a crucial role in stimulating the production of sex hormones, particularly testosterone and estrogen. In research settings, HCG has been studied for its ability to:

• Stimulate testosterone production by mimicking luteinizing hormone (LH)
• Support spermatogenesis and fertility-related functions
• Maintain testicular size and function in prolonged androgen therapy research
• Potentially aid in weight regulation by influencing metabolic activity
• Modulate endocrine function in hormone-related studies

HCG is commonly investigated in endocrinology and reproductive research due to its ability to regulate hormone production and influence metabolic processes.

RESEARCH

HCG and Testosterone Production

HCG interacts with luteinizing hormone receptors in the Leydig cells of the testes, promoting the production of testosterone. Studies indicate that:

• HCG mimics LH, stimulating natural testosterone synthesis.
• It may help preserve testicular function during long-term anabolic hormone research.
• Research suggests it plays a role in hormone balance and androgen regulation.

HCG and Fertility Research

HCG has been extensively studied for its potential role in male and female fertility. Findings include:

• Stimulation of sperm production in hypogonadal models.
• Induction of ovulation in reproductive studies.
• Potential restoration of endogenous hormone balance after exogenous hormone exposure.

HCG and Weight Regulation

Some research has explored HCG’s potential effects on metabolism and fat distribution. Studies suggest:

• It may influence fat mobilization during periods of caloric restriction.
• Potential interactions with the hypothalamic-pituitary-adrenal (HPA) axis that affect metabolic function.
• Further studies are needed to understand its role in adipose tissue regulation.

HCG and Endocrine Function

Beyond reproductive health, HCG has been investigated for its role in overall endocrine system modulation. Research indicates:

• It may support adrenal function by interacting with steroidogenic pathways.
• Potential applications in research related to thyroid function and metabolic balance.
• Its structural similarity to other glycoprotein hormones suggests possible cross-signaling effects.

STRUCTURE

• Molecular Formula: C₁₀₅H₁₆₉N₂₇O₃₂
• Molecular Weight: 2,321.6 g/mol
• CAS Registry Number: 9002-61-3
• Purity: 99% HPLC

RESEARCH USE ONLY

HCG is strictly intended for research and laboratory purposes. It is not for human or veterinary use and is not intended for therapeutic or diagnostic applications.