OVERVIEW

CJC-1295 Without DAC is a synthetic growth hormone-releasing hormone (GHRH) analog designed to increase endogenous growth hormone (GH) and insulin-like growth factor-1 (IGF-1) levels. Initially developed for medical applications, CJC-1295 has gained attention in research due to its ability to:

• Stimulate GH secretion and prolong its half-life
• Enhance protein synthesis and muscle growth
• Support fat metabolism and improve body composition
• Promote cellular repair and longevity
• Improve sleep quality and cognitive function

Unlike CJC-1295 with DAC (Drug Affinity Complex), which provides sustained GH release, the version without DAC offers a more natural pulsatile release pattern, closely mimicking physiological GH secretion.

RESEARCH

CJC-1295 and Growth Hormone Secretion

CJC-1295 Without DAC functions by binding to the growth hormone-releasing hormone receptor (GHRHR) in the pituitary gland, leading to an increase in GH release. Studies suggest that:

• GH pulsatility is essential for muscle growth, metabolic regulation, and overall physiological balance.
• CJC-1295 without DAC enhances GH release without significantly affecting prolactin levels.
• Research indicates that combining CJC-1295 without DAC with a GH secretagogue like Ipamorelin may amplify its effects.

CJC-1295 and Muscle Growth & Recovery

As an essential regulator of GH, CJC-1295 has been studied for its potential role in enhancing muscle repair, protein synthesis, and strength development. Key findings include:

• Increased lean muscle mass and reduction in fat mass.
• Faster muscle recovery after intense exercise or injury.
• Potential benefits in age-related muscle wasting conditions.

CJC-1295 and Fat Metabolism

Growth hormone is known to influence lipid metabolism, and research on CJC-1295 suggests:

• Enhanced lipolysis, leading to improved fat loss.
• Regulation of adipose tissue distribution, supporting a leaner physique.
• Increased metabolic rate, contributing to better energy balance.

CJC-1295 and Anti-Aging Research

CJC-1295 Without DAC has been explored for its role in longevity and cellular repair. Research indicates:

• Enhanced collagen production, potentially improving skin elasticity and joint health.
• Cellular regeneration and neuroprotection, which may benefit cognitive function.
• Improved sleep cycles due to its influence on deep sleep stages.

STRUCTURE

• Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
• Molecular Weight: 3367.9 g/mol
• CAS Registry Number: 863288-34-0
• Purity: 99% HPLC

RESEARCH USE ONLY

CJC-1295 Without DAC is strictly intended for research and laboratory purposes. It is not for human or veterinary use and is not intended for therapeutic or diagnostic applications.